Melanopsin & ipRGCs
In 2002, Provencio discovered melanopsin — a photopigment in a small subset of retinal ganglion cells (ipRGCs). These cells do not help you see images. They measure ambient light and send a direct signal to the suprachiasmatic nucleus, the brain's master clock.
The ipRGC action spectrum peaks near 480 nm — cyan blue. A 470 nm LED at ~100 lux is roughly 100 melanopic-EDI, enough to shift phase. This is the basis for the CIE S 026:2018 standard used throughout SunCycle.